Product Details

Appearance:Fine Powder

Throughput:10|Metric Ton|Month

Application:antidiabetic

Delivery Time:3-5working days

Gliquidone is an oral hypoglycemic agent, and was called as the second generation sulfonylurea oral hypoglycemic drug together with glyburide, gliclazide and glipizide, primarily for the treatment of non-insulin-dependent (namely, II type) diabetes. Its mechanism of action is the same as other sulfonylurea drugs and can stimulate insulin secretion from pancreatic β cells, and can enhance the action of insulin, enhance the sensitivity of tissues to insulin action, increase the number of insulin receptor and strengthen post-receptor action of insulin. During the early phase of treatment, it is mainly used for promoting the secretion of endogenous insulin; after a period of time of treatment, its main role is to improve the sensitivity of peripheral tissues to insulin. Diabetic nephropathy is one of the late complications of diabetes while gliquidone is the only sulfonylurea drugs that not affected by renal function and therefore can be applied to diabetic patients with impaired renal function. It is the primary-choice of drug for the treatment of patients of non-insulin dependent diabetes accompanied with insufficiency of renal function. Gliquidone is characterized by short duration of action and seldom undergoing of renal excretion with a small dose being able to control postprandial blood glucose. Oral absorption is quick and complete. After the first oral administration of 30mg, the plasma concentration reaches its peak value, 500~700μg/L after 2 to 3 hours. The efficacy onset occurs at 1 hour after administration, the maximal effect can be extended up to 2 to 3 hours with the duration of 8 hours and the plasma protein binding rate being 99% and the half-life of about 1.5 hours. It is mainly metabolized in the liver through hydroxylation or demethylation with its metabolites having no significant hypoglycemic activity and most of them being discharged through feces via biliary while only 5% being subject to renal excretion. This product has mild effect and can be subject to dose adjustment timely based on blood sugar or urine glucose and rarely cause hypoglycemia reaction. It is suitable for the treatment of adult-type mild, moderate diabetes which can’t be simply treated through diet, especially for patients with renal insufficiency.

Q&A.

Q1:Can I get a sample
A: Of course. For most products we can provide a free sample, while the shipping cost should undertake by your side.
 

Q2:What’s your MOQ
A:Mostly MOQ is 1kg, but we also accept less quantity like 100g on the condition that a sample charge is 100% paid.
 

Q3:Do you accept VISA business credit card
A:Sorry we don’t accept VISA credit card,we’d like to accept T/T, Western Union or Paypal

Q4: What’s your delivery time
A:We will make delivery within 3 to 5 days after payment confirmed (Chinese holiday are not included).
 

Q5:How long does it take to the goods arrived

A:It is Depending on your location,
For small order, please expect 5-7 days by DHL,UPS,TNT, FEDEX, EMS.
For mass order, please allow 5-8 days by Air, 20-35 days by Sea.
 

Q6:How do you treat quality complaint
A:First of all, our QC department will do strict examination of our export products by HPLC, UV, GC , TLC and so on in order to reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.

If you would like to order goods from our company,below process for your reference.

1,Choose the items that you are interested in,and the quantity you would like to order with each items,then send your inquiry to us by email or fax.Make sure that you have an accurate contact method especially a workable email address.If you need to know the shipping cost,pls let us know the name of the international port close to you.
2,We will reply you within 24hours.Again,your detail description on the potential order and your business background would be very helpful to an efficient reply.
3,You can have free samples up to US$5 in value.Any sample required beyond this value will be charged.Also you are required o pay for the sample delivery cost by courier(DHL,UPS,TNT,Fedex,EMS..)
4,Once you confirmed the order content,we will send you a proforma invocie (include the products no,quantity,price,freight charge,total amount and bank info.).After you confirmed this PI and send us the feedback and the bank transfer proof,we will arrange this order.
5,Once the payment has confirmed,we will ship the goods to you as soon as possible.
6,After delivery the goods,for courier we will give you one tracking no.and told you how to track it on the internet.
For sea,we will fax or send you the B/L or the file that you needed.
For air,we will fax you the airway bill.　
Please read all terms before purchasing, by purchasing this product you agree to all terms.
For oversea shipping,it's need the import tax.pls contact with your local courier.