Natural Extracted Baicalein 98% HPLC

  • Cas No.:491-67-8
  • Molecular Formula:C15H10O5
  • Purity:95% 98%
  • Molecular Weight:
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Product Details

Appearance:Fine Powder

Throughput:10|Metric Ton|Month

Application:Medicine and health products.

Delivery Time:3-5working days

BASIC INFORMATION

Product Name:

Baicalein

Synonyms:

BAICALEIN(SH)NOW RG GRADE;Baicalein, monohydrate, 5,6,7-Trihydroxy-2-phenyl-4H-chromen-4-one monohydrate;Baicelein;Noroxylin;5,6,7-trihydroxy-2-phenyl-4H-chroMen-4-one;Baicalein 98%;5,6,7-trihydroxy-2-phenyl-4-chromenone hydrate;Baicaleine

CAS:

491-67-8

MF:

C15H10O5

MW:

270.24

Melting point 

256-271 °C(lit.)

Boiling point 

373.35°C (rough estimate)

FUNCTION

Baicalein is a flavonoid originally isolated from the roots of Scutellaria baicalensis Georgi. Several different functions of baicalein have been reported. Platelet 12-lipoxygenase is inhibited by baicalein with an ID50 value of 0.12 μM, with minimal inhibition of platelet cyclooxygenase-1 (IC50 = 0.83 mM). Baicalein inhibits lipid peroxidation, as assessed by production of TBARS, with an IC50 value of 5 μM. In addition to these effects, baicalein may play a role in apoptosis, as the compound inhibits cell growth of three human hepatocellular carcinoma cell lines with IC50 values ranging from 17-70 μg/ml.